SCHEMBL22633784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL824255	0.86	MEN1 (0.46)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL4585510	0.86	MEN1 (0.46)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL29948098	0.85	PDK2 (0.45)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL3038890	0.85	PDK2 (0.53)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL390934	0.85	PDK2 (0.45)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL31483494	0.85	PDK2 (0.53)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL824239	0.84	PDK2 (0.57)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL19759995	0.81	PDK2 (0.43)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL18032791	0.80	KDM4E (0.44)	MEN1KMT2APDK2OPRM1OPRD1
	SCHEMBL13819624	0.78	PDK2 (0.41)	MEN1KMT2APDK2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.