SCHEMBL824239

SCHEMBL824239

OC1(c2ccccc2)c2ccccc2-c2ccc(Br)cc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 8/20 0.57
OPRM1 P35372 1/20 0.47
OPRD1 P41143 1/20 0.47
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
THRB P10828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
P2RX1 P51575 1/20 0.38
P2RX3 P56373 1/20 0.38
P2RX4 Q99571 1/20 0.38
P2RX7 Q99572 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
PTPRC P08575 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3038890 0.95 PDK2 (0.53) PDK2OPRM1OPRD1MEN1KMT2A
SCHEMBL31483494 0.95 PDK2 (0.53) PDK2OPRM1OPRD1MEN1KMT2A
SCHEMBL28607030 0.88 PDK2 (0.49) PDK2OPRM1OPRD1THRBTDP1
SCHEMBL22071209 0.87 PDK2 (0.51) PDK2OPRM1OPRD1MEN1KMT2A
SCHEMBL26547760 0.87 PDK2 (0.55) PDK2OPRM1OPRD1
SCHEMBL19760035 0.86 PDK2 (0.50) PDK2OPRM1OPRD1MEN1KMT2A
SCHEMBL824160 0.85 PDK2 (0.55) PDK2OPRM1OPRD1THRBTDP1
SCHEMBL30463510 0.85 PDK2 (0.55) PDK2OPRM1OPRD1THRBTDP1
SCHEMBL1978583 0.85 PDK2 (0.55) PDK2OPRM1OPRD1THRBTDP1
SCHEMBL13137374 0.85 PDK2 (0.47) PDK2OPRM1OPRD1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613323-A 9-Phenylfluorene compound with piezochromic luminescence property 南京邮电大学 2025-03-14 CN claimed
CN-113582823-B Preparation method of 2-amino-9,9-diphenylfluorene 河北凡克新材料有限公司 2023-04-07 CN claimed
CN-113582823-A Preparation method of 2-amino-9, 9-diphenylfluorene 河北凡克新材料有限公司 2021-11-02 CN claimed
CN-105085163-B Synthesis method of 2-bromo-9,9-diphenylfluorene 河南省商业科学研究所有限责任公司 2017-04-12 CN claimed
CN-105085162-B One kettle way prepares 2 bromine, 9,9 diphenylfluorene 河南省商业科学研究所有限责任公司 2017-04-05 CN claimed
CN-105016968-B A kind of synthetic method of 2 bromine, 9,9 diphenylfluorene 河南省商业科学研究所有限责任公司 2017-04-05 CN claimed
CN-105085162-A One-pot method for preparing 2-bromo-9,9-diphenylfluorene HENAN BUSINESS RES INST CO LTD 2015-11-25 CN claimed
CN-105085163-A Synthesis method of 2-bromo-9,9-diphenylfluorene HENAN BUSINESS RES INST CO LTD 2015-11-25 CN claimed
CN-105016968-A Synthetic method of 2-bromo-9,9-diphenyl fluorene HENAN BUSINESS RES INST CO LTD 2015-11-04 CN claimed
CN-119613323-A 9-Phenylfluorene compound with piezochromic luminescence property 南京邮电大学 2025-03-14 CN disclosed
US-20240244963-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2024-07-18 US disclosed
US-20240244963-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2024-07-18 US disclosed
EP-3514140-B1 FLUORINE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME AND METHOD FOR PREPARING SAME LG CHEMICAL LTD (KR) 2024-03-06 EP disclosed
US-11845824-B2 Same novel polymer and organic light emitting device comprising the same LG CHEM, LTD. 2023-12-19 US disclosed
EP-1862524-A1 Organic light emitting device and flat panel display device comprising the same Samsung SDI Co., Ltd. (KR) 2007-12-05 EP disclosed
US-20070231503-A1 Organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-10-04 US disclosed
US-20070231503-A1 Organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-10-04 US disclosed
CN-1315764-C Conjugate derivative material of 9-phenyl-9-pyrenyl fluorene substituted pyrene its preparation method and application UNIV FUDAN (CN) 2007-05-16 CN disclosed
CN-1785943-A Conjugate derivative material of 9-phenyl-9-pyrenyl fluorene substituted pyrene its preparation method and application UNIV FUDAN (CN) 2006-06-14 CN disclosed
CN-1686976-A Conjugated ramification material of fluorine containing anthracene and pyrene at 9th position, preparation method and application UNIV FUDAN (CN) 2005-10-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240244963-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, PPOX, CYP2C19 PDK2 223/4885OPRM1 3321/4885OPRD1 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.