Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.74 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953079 | 1.00 | ATM (0.85) | ATMCYP2D6CYP2C19KCNH2CACNA1G | |
| SCHEMBL11738962 | 0.96 | ATM (0.78) | ATMCYP2D6CYP2C19KCNH2CACNA1G | |
| SCHEMBL11744068 | 0.96 | ATM (0.78) | ATMCYP2D6CYP2C19KCNH2CACNA1G | |
| SCHEMBL11745028 | 0.94 | ATM (0.75) | ATMCYP2D6CYP2C19KCNH2CACNA1G | |
| SCHEMBL11365346 | 0.92 | KCNH2 (0.86) | ATMCYP2D6CYP2C19KCNH2CACNA1G | |
| SCHEMBL20437921 | 0.85 | KMT2A (0.94) | ATMCYP2D6CYP2C19KDM4EPOLB | |
| SCHEMBL7297907 | 0.85 | KCNH2 (0.71) | ATMCYP2D6CYP2C19KCNH2CACNA1G | |
| SCHEMBL7953122 | 0.85 | TSHR (0.85) | ATMCYP2D6CYP2C19KDM4EPOLB | |
| SCHEMBL22640122 | 0.85 | TSHR (0.85) | ATMCYP2D6CYP2C19KDM4EPOLB | |
| SCHEMBL10982797 | 0.85 | ATM (0.85) | ATMCYP2D6CYP2C19KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | ATM 3431/4885CYP2D6 3360/4885CYP2C19 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.