Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LDHA | P00338 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | NPY2R | P49146 | 1/20 | 0.60 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639884 | 1.00 | LMNA (0.70) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL22639821 | 0.88 | ABCB1 (0.67) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL16392428 | 0.88 | ABCB1 (0.67) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL10991486 | 0.83 | GAA (0.68) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL10982308 | 0.83 | GAA (0.68) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL7600203 | 0.82 | KMT2A (1.00) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL16938190 | 0.79 | ABCB1 (0.68) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 | |
| SCHEMBL22640119 | 0.78 | CYP1A2 (0.79) | LMNAKMT2AMEN1ABCB1ALDH1A1 | |
| SCHEMBL11538237 | 0.78 | CYP1A2 (0.79) | LMNAKMT2AMEN1ABCB1ALDH1A1 | |
| SCHEMBL31510212 | 0.78 | KMT2A (0.89) | LMNAKMT2AMEN1SMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | LMNA 769/4885KMT2A 4613/4885MEN1 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.