Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22642833 | 1.00 | PREP (0.56) | PREPCHRM2CHRM1CHRM3CTSK | |
| SCHEMBL22642834 | 1.00 | PREP (0.56) | PREPCHRM2CHRM1CHRM3CTSK | |
| SCHEMBL22643140 | 1.00 | PREP (0.56) | PREPCHRM2CHRM1CHRM3CTSK | |
| SCHEMBL19186799 | 1.00 | PREP (0.56) | PREPCHRM2CHRM1CHRM3CTSK | |
| SCHEMBL22643297 | 1.00 | PREP (0.56) | PREPCHRM2CHRM1CHRM3CTSK | |
| SCHEMBL22643111 | 1.00 | PREP (0.56) | PREPCHRM2CHRM1CHRM3CTSK | |
| SCHEMBL22642849 | 0.83 | PREP (0.56) | PREPCHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL22643309 | 0.83 | PREP (0.56) | PREPCHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL22643143 | 0.83 | PREP (0.56) | PREPCHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL13910744 | 0.82 | PREP (0.64) | PREPCHRM2CHRM1CHRM3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970283-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2020-11-11 | — | — | EP | disclosed |