Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453949 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2PDE4DAXLMEN1PSIP1 | |
| SCHEMBL3977541 | 0.70 | CHRNB4 (0.38) | PDE4DAXLMEN1PSIP1MKNK1 | |
| SCHEMBL5681756 | 0.70 | MEN1 (0.48) | SMN1; SMN2MEN1CFTRGOPCGAA | |
| SCHEMBL17064640 | 0.68 | SMN1; SMN2 (0.65) | SMN1; SMN2AXLMEN1PSIP1MKNK1 | |
| SCHEMBL8545068 | 0.68 | CYP17A1 (0.58) | SMN1; SMN2PDE4DCFTRSLC6A2SLC6A4 | |
| SCHEMBL28478132 | 0.67 | ALDH1A1 (0.41) | SMN1; SMN2MEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31090354 | 0.66 | SMN1; SMN2 (0.72) | SMN1; SMN2AXLMEN1PSIP1MKNK1 | |
| SCHEMBL27593798 | 0.66 | KDM4E (0.40) | SMN1; SMN2MEN1SLC6A2SLC6A3GAA | |
| SCHEMBL5684882 | 0.66 | AXL (0.59) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL9161522 | 0.66 | MEN1 (0.40) | SMN1; SMN2MEN1SLC6A2SLC6A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011085140-A1 | THICKENED HAIR COLOURANT AND BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| US-7204861-B2 | Hair coloring compositions | THE PROCTER & GAMBLE COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| US-20040237218-A1 | Hair colouring compositions | WELLA OPERATIONS US, LLC | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237218-A1 | Hair colouring compositions | COXFA4L2, CYBA, MT-CO3 | SMN1; SMN2 3041/4885PDE4D 2415/4885AXL 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.