Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | CTSC | P53634 | 5/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078754 | 1.00 | DPP4 (0.38) | DPP4USP30AAK1XIAPCTSK | |
| SCHEMBL21076266 | 0.90 | USP30 (0.37) | DPP4USP30AAK1XIAPP2RX7 | |
| SCHEMBL22643259 | 0.86 | CTSC (0.44) | CTSKCTSC | |
| SCHEMBL16064471 | 0.86 | CTSC (0.44) | CTSKCTSC | |
| SCHEMBL16064115 | 0.84 | PREP (0.42) | DPP4USP30AAK1XIAPP2RX7 | |
| SCHEMBL18643728 | 0.84 | PREP (0.42) | DPP4USP30AAK1XIAPP2RX7 | |
| SCHEMBL22642934 | 0.77 | CCKBR (0.47) | DPP4USP30AAK1XIAPCTSK | |
| SCHEMBL19368351 | 0.77 | CTSC (0.40) | CTSKCTSC | |
| SCHEMBL16078799 | 0.77 | PREP (0.40) | DPP4USP30AAK1SCN9A | |
| SCHEMBL22642842 | 0.77 | PREP (0.40) | DPP4USP30AAK1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970283-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2020-11-11 | — | — | EP | disclosed |