Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56908 | 0.94 | LMNA (0.58) | LMNAADRB2ADRB1ADRB3TSHR | |
| Ethylamine SCHEMBL23658205 | 0.92 | LMNA (0.52) | LMNAADRB2ADRB1ADRB3TSHR | |
| Fluoride SCHEMBL27440512 | 0.92 | LMNA (0.56) | LMNATSHRTHRB | |
| Water SCHEMBL27547819 | 0.92 | LMNA (0.56) | LMNATSHRTHRB | |
| Hydrochloric Acid SCHEMBL3921975 | 0.92 | LMNA (0.56) | LMNATSHRTHRB | |
| Ammonia Solution, Strong SCHEMBL8489442 | 0.92 | LMNA (0.56) | LMNATSHRTHRB | |
| Hydrogen Sulfide SCHEMBL28072106 | 0.92 | LMNA (0.61) | LMNATSHRTHRB | |
| Hexane SCHEMBL9853221 | 0.92 | LMNA (0.61) | LMNATSHRTHRB | |
| Ethylenediamine SCHEMBL27500208 | 0.90 | LMNA (0.50) | LMNAADRB2ADRB1ADRB3TSHR | |
| SCHEMBL10336779 | 0.89 | LMNA (0.54) | LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463493-B | Polymeric substrate having a surface with reduced biomolecule adhesion and thermoplastic articles of such substrate | SIO2医药产品公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-103554168-B | Epoxy radicals silicone hydride, its preparation method and the curable compositions comprising it | 莫门蒂夫性能材料股份有限公司 | 2017-07-18 | — | — | CN | disclosed |
| EP-2137198-B1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-05-18 | — | — | EP | disclosed |
| US-7989651-B2 | trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-02 | — | — | US | disclosed |
| EP-2137198-A1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | Momentive Performance Materials Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008112150-A1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-09-18 | — | — | WO | disclosed |
| US-20080221238-A1 | Epoxysilanes, processes for their manufacture and curable compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-11 | — | — | US | disclosed |