Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1266666 | 0.91 | HCRTR2 (0.40) | HCRTR2EPHX1KMT2ANPSR1MEN1 | |
| SCHEMBL12070332 | 0.91 | HCRTR2 (0.40) | HCRTR2EPHX1KMT2ANPSR1MEN1 | |
| SCHEMBL754567 | 0.91 | HCRTR2 (0.40) | HCRTR2EPHX1KMT2ANPSR1MEN1 | |
| SCHEMBL13840040 | 0.83 | HCRTR2 (0.38) | HCRTR2EPHX1HPGDKMT2ANPSR1 | |
| SCHEMBL28291895 | 0.82 | HPGD (0.49) | EPHX1HPGDKMT2ASMN1; SMN2USP2 | |
| SCHEMBL11888344 | 0.82 | HPGD (0.49) | EPHX1HPGDKMT2ASMN1; SMN2USP2 | |
| SCHEMBL4911658 | 0.80 | SMN1; SMN2 (0.54) | HPGDKMT2ASMN1; SMN2USP2TP53 | |
| SCHEMBL4911660 | 0.80 | SMN1; SMN2 (0.54) | HPGDKMT2ASMN1; SMN2USP2TP53 | |
| SCHEMBL25961852 | 0.80 | SMN1; SMN2 (0.54) | HPGDKMT2ASMN1; SMN2USP2TP53 | |
| SCHEMBL28662052 | 0.78 | HCRTR2 (0.45) | HCRTR2EPHX1HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227168-A1 | INHIBITING TRABID | INTEGRAL EARLY DISCOVERY, INC. (US) | 2020-11-12 | — | — | WO | disclosed |