Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888344 | 1.00 | HPGD (0.49) | HPGDSMN1; SMN2HTTUSP2KMT2A | |
| SCHEMBL4911660 | 0.95 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2HTTUSP2KMT2A | |
| SCHEMBL4911658 | 0.95 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2HTTUSP2KMT2A | |
| SCHEMBL25961852 | 0.95 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2HTTUSP2KMT2A | |
| SCHEMBL28662052 | 0.91 | HCRTR2 (0.45) | HPGDSMN1; SMN2HTTUSP2KMT2A | |
| SCHEMBL28662054 | 0.91 | HCRTR2 (0.45) | HPGDSMN1; SMN2HTTUSP2KMT2A | |
| SCHEMBL22644684 | 0.82 | HCRTR2 (0.38) | HPGDSMN1; SMN2USP2KMT2AMEN1 | |
| SCHEMBL28458597 | 0.82 | HCRTR2 (0.41) | SMN1; SMN2USP2KMT2AMEN1EPHX1 | |
| SCHEMBL21607282 | 0.82 | HCRTR2 (0.41) | SMN1; SMN2USP2KMT2AMEN1EPHX1 | |
| SCHEMBL1066501 | 0.81 | EPHX1 (0.41) | HPGDSMN1; SMN2HTTUSP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-B | Modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109563103-A | modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2019-04-02 | — | — | CN | disclosed |