Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19869711 | 0.77 | BRD4 (0.54) | BRD4BRD9 | |
| SCHEMBL18497012 | 0.75 | BRD4 (0.58) | BRD4 | |
| SCHEMBL19869747 | 0.73 | ASIC3 (0.52) | BRD4BRD9 | |
| SCHEMBL19869753 | 0.73 | BRD4 (0.49) | BRD4BRD9 | |
| SCHEMBL19857677 | 0.72 | BRD4 (0.55) | BRD4BRD9 | |
| SCHEMBL27263483 | 0.71 | BRD4 (0.54) | BRD4BRD9 | |
| SCHEMBL19142112 | 0.71 | PARP10 (0.42) | — | |
| SCHEMBL18497022 | 0.70 | BRD4 (0.58) | BRD4 | |
| SCHEMBL24556579 | 0.69 | BRD4 (0.73) | BRD4BRD9 | |
| SCHEMBL19869845 | 0.68 | BRD4 (0.50) | BRD4BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836742-B2 | N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals | NEOMED INSTITUTE (CA) | 2020-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836742-B2 | N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals | BRD4, BRDT, BRD1 | BRD4 1/4885BRD9 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.