Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34469179 | 1.00 | CMA1 (0.47) | CMA1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL22645709 | 1.00 | CMA1 (0.47) | CMA1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL20833763 | 1.00 | CMA1 (0.47) | CMA1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL22661096 | 1.00 | CMA1 (0.47) | CMA1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL34469032 | 0.80 | EHMT2 (0.50) | CMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL22518781 | 0.80 | EHMT2 (0.50) | CMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL22493942 | 0.80 | EHMT2 (0.50) | CMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL25402036 | 0.75 | CMA1 (0.45) | CMA1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL17360678 | 0.72 | EHMT2 (0.61) | CMA1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL17360659 | 0.72 | CMA1 (0.56) | CMA1GSK3AGSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4410773-A2 | PROCESS FOR THE SYNTHESIS OF (S) 3-AMINO-4-(DIFLUOROMETHYLENYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID | Northwestern University (US) | 2024-08-07 | — | — | EP | disclosed |
| EP-3784649-B1 | PROCESS FOR THE SYNTHESIS OF (S)-3-AMINO-4-(DIFLUOROMETHYLENYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID | UNIV NORTHWESTERN (US) | 2024-07-31 | — | — | EP | disclosed |
| CN-117550990-A | Process for the synthesis of (S) -3-amino-4- (difluoromethylene) cyclopent-1-ene-1-carboxylic acid | 西北大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117550991-A | Process for the synthesis of (S) -3-amino-4- (difluoromethylene) cyclopent-1-ene-1-carboxylic acid | 西北大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-112513006-B | Process for the synthesis of (S) -3-amino-4- (difluoromethylene) cyclopent-1-ene-1-carboxylic acid | 西北大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-112513006-A | Process for the synthesis of (S) -3-amino-4- (difluoromethylene) cyclopent-1-ene-1-carboxylic acid | 西北大学 | 2021-03-16 | — | — | CN | disclosed |
| US-10836708-B2 | Process for the synthesis of (s) 3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid | NORTHWESTERN UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836708-B2 | Process for the synthesis of (s) 3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid | SULT1E1, QPCT, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CMA1 135/4885GSK3A 3427/4885GSK3B 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.