Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18665197 | 1.00 | MAPT (0.49) | MAPTMAPK1EPHX2PRKCAPRKCE | |
| SCHEMBL18665089 | 1.00 | MAPT (0.49) | MAPTMAPK1EPHX2PRKCAPRKCE | |
| SCHEMBL20892181 | 1.00 | MAPT (0.49) | MAPTMAPK1EPHX2PRKCAPRKCE | |
| SCHEMBL18641714 | 1.00 | MAPT (0.49) | MAPTMAPK1EPHX2PRKCAPRKCE | |
| SCHEMBL26319645 | 0.93 | MAPK1 (0.48) | MAPTMAPK1EPHX2PRKCAPRKCE | |
| SCHEMBL26319651 | 0.93 | MAPK1 (0.48) | MAPTMAPK1EPHX2PRKCAPRKCE | |
| SCHEMBL24163833 | 0.91 | MAPK1 (0.58) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL25411427 | 0.91 | MAPK1 (0.58) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL21842903 | 0.91 | MAPK1 (0.58) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL25410411 | 0.91 | MAPK1 (0.58) | MAPTMAPK1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227537-A1 | DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION | Modernatx, Inc (US) | 2020-11-12 | — | — | WO | disclosed |