Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 4/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26319651 | 1.00 | MAPK1 (0.48) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL18665089 | 0.93 | MAPT (0.49) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL18665197 | 0.93 | MAPT (0.49) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL22646140 | 0.93 | MAPT (0.49) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL20892181 | 0.93 | MAPT (0.49) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL18641714 | 0.93 | MAPT (0.49) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL26734015 | 0.93 | MAPT (0.48) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL26735135 | 0.93 | MAPT (0.48) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL26735108 | 0.93 | MAPT (0.48) | MAPK1MAPTEPHX2LMNAALDH1A1 | |
| SCHEMBL29292166 | 0.91 | MAPK1 (0.57) | MAPK1MAPTLMNAALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270685-A1 | POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE | MODERNATX, INC. (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270685-A1 | POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE | POLM, EMG1, MCM6 | MAPK1 4072/4885MAPT 3723/4885EPHX2 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.