SCHEMBL226465

SCHEMBL226465

c1ccc2sc(Cc3nc4ccccc4s3)nc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBE2T Q9NPD8 1/20 0.70
ASIC3 Q9UHC3 1/20 0.70
MAPT P10636 5/20 0.60
KMT2A Q03164 4/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
MEN1 O00255 2/20 0.60
ALDH1A1 P00352 2/20 0.60
HTT P42858 2/20 0.60
KDM4E B2RXH2 1/20 0.60
LMNA P02545 1/20 0.60
POLB P06746 1/20 0.60
GAA P10253 1/20 0.60
SMN1; SMN2 Q16637 8/20 0.59
RAB9A P51151 6/20 0.59
NPC1 O15118 5/20 0.59
MAPK1 P28482 1/20 0.59
HPGD P15428 3/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2D6 P10635 1/20 0.57
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7601035 0.98 UBE2T (0.68) UBE2TASIC3MAPTKMT2AL3MBTL1
Fluoride SCHEMBL7600822 0.96 UBE2T (0.66) UBE2TASIC3MAPTKMT2AL3MBTL1
SCHEMBL7600826 0.92 UBE2T (0.61) UBE2TASIC3MAPTKMT2AL3MBTL1
SCHEMBL1127709 0.88 UBE2T (0.61) UBE2TASIC3MAPTKMT2AL3MBTL1
SCHEMBL19372016 0.86 UBE2T (0.70) UBE2TASIC3MAPTL3MBTL1ALDH1A1
SCHEMBL6229545 0.84 SMN1; SMN2 (0.56) UBE2TASIC3MAPTKMT2AL3MBTL1
SCHEMBL24426123 0.83 UBE2T (0.51) UBE2TASIC3MAPTKMT2AL3MBTL1
SCHEMBL12596792 0.83 PIK3CA (0.58) UBE2TASIC3MAPTKMT2AL3MBTL1
SCHEMBL2791997 0.83 UBE2T (0.66) UBE2TASIC3MAPTKMT2AL3MBTL1
SCHEMBL244157 0.83 UBE2T (0.66) UBE2TASIC3MAPTKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478196-B Fluoroboron compound, preparation method and application thereof, and mitochondrion targeting photosensitizer 南京工业大学 2025-05-13 CN claimed
CN-116478196-A Fluoroboron compound, preparation method and application thereof, and mitochondrion targeting photosensitizer 南京工业大学 2023-07-25 CN claimed
US-8182718-B2 Ligand exchange thermochromic systems and high ε ligands for same PLEOTINT, L.L.C. (US) 2012-05-22 US claimed
US-6821786-B2 HOME/SELF-DIAGNOSIS; MICROTRACINGS FUTURE DATA INC. 2004-11-23 US claimed
CN-116478196-B Fluoroboron compound, preparation method and application thereof, and mitochondrion targeting photosensitizer 南京工业大学 2025-05-13 CN disclosed
CN-116478196-B Fluoroboron compound, preparation method and application thereof, and mitochondrion targeting photosensitizer 南京工业大学 2025-05-13 CN disclosed
CN-119606885-A Mitochondrial targeting photoresponse nano-agonist and preparation method and application thereof 江苏师范大学 2025-03-14 CN disclosed
CN-115348979-B Methacrylic copolymer, composition, molded body, method for producing film or sheet, and laminate 株式会社可乐丽 2024-10-22 CN disclosed
CN-118598821-A Tri-substituted ethylene synthesis method based on alkylene transfer strategy 复旦大学 2024-09-06 CN disclosed
EP-3581609-B1 ACRYLIC RESIN BIAXIALLY STRETCHED FILM AND METHOD FOR MANUFACTURING THE SAME KURARAY CO (JP) 2023-08-02 EP disclosed
CN-116478196-A Fluoroboron compound, preparation method and application thereof, and mitochondrion targeting photosensitizer 南京工业大学 2023-07-25 CN disclosed
EP-4130058-A1 METHACRYLIC COPOLYMER, COMPOSITION, SHAPED OBJECT, METHOD FOR PRODUCING FILM OR SHEET, AND LAYERED PRODUCT Kuraray Co., Ltd. (JP) 2023-02-08 EP disclosed
US-5424181-A High-sensitivity silver halide emulsions without antifogging agents EASTMAN KODAK COMPANY (US) 1995-06-13 US disclosed
EP-0618484-A1 Process for preparing photographic emulsions having a low fog level KODAK-PATHE (FR) 1994-10-05 EP disclosed
EP-0352618-B1 Stabilized photographic recording material EASTMAN KODAK CO (US) 1994-05-04 EP disclosed
EP-0352618-A1 Stabilized photographic recording material EASTMAN KODAK COMPANY (US) 1990-01-31 EP disclosed
US-4885233-A ANTIFOGGING AGENT EASTMAN KODAK COMPANY (US) 1989-12-05 US disclosed
US-4256896-A THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES CIBA-GEIGY AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
US-4097484-A ORGANIC PIGMENTS, PLASTICS CIBA-GEIGY CORPORATION (US) 1978-06-27 US disclosed
US-4002635-A FOR COLORING PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1977-01-11 US disclosed