Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541876 | 0.80 | CYP1A2 (0.61) | CYP1A2IFNAR1ALDH1A1MAPK1LMNA | |
| SCHEMBL31167972 | 0.78 | IFNAR1 (0.60) | CYP1A2IFNAR1ALDH1A1MAPK1LMNA | |
| SCHEMBL577858 | 0.78 | IFNAR1 (0.60) | CYP1A2IFNAR1ALDH1A1MAPK1LMNA | |
| SCHEMBL22647159 | 0.77 | KDM4E (0.47) | CDK2ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL30548749 | 0.75 | IFNAR1 (0.58) | CYP1A2IFNAR1ALDH1A1MAPK1LMNA | |
| SCHEMBL7191375 | 0.75 | CYP1A2 (0.54) | CYP1A2IFNAR1ALDH1A1MAPK1LMNA | |
| SCHEMBL16431316 | 0.73 | DBH (0.44) | CDK2ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL7482207 | 0.72 | IFNAR1 (0.51) | CYP1A2IFNAR1ALDH1A1MAPK1LMNA | |
| SCHEMBL24121632 | 0.71 | CDK2 (0.41) | CDK2ALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL2434774 | 0.70 | PTPN22 (0.58) | CYP1A2ALDH1A1POLBHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227180-A1 | SULFUR AND AMIDE TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USES THEREFOR | SAINT LOUIS UNIVERSITY (US) | 2020-11-12 | — | — | WO | disclosed |