SCHEMBL577858

SCHEMBL577858

c1ccc2c(Sc3cccc4ccccc34)cccc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IFNAR1 P17181 1/20 0.60
ALDH1A1 P00352 6/20 0.58
LMNA P02545 3/20 0.58
MAPK1 P28482 2/20 0.58
NPY1R P25929 1/20 0.58
NPY2R P49146 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.50
CYP2A6 P11509 3/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 1/20 0.50
RAD52 P43351 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TYMS P04818 2/20 0.46
RECQL P46063 1/20 0.46
PDGFRB P09619 1/20 0.46
CYP1A2 P05177 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31167972 1.00 IFNAR1 (0.60) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL30548749 0.97 IFNAR1 (0.58) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL7482207 0.89 IFNAR1 (0.51) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL20222284 0.87 IFNAR1 (0.50) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL6443221 0.87 IFNAR1 (0.50) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL31490493 0.85 IFNAR1 (0.49) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL30544440 0.85 HPRT1 (0.64) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL2890325 0.85 IFNAR1 (0.49) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL2944062 0.85 HPRT1 (0.64) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL7541876 0.85 CYP1A2 (0.61) IFNAR1ALDH1A1LMNAMAPK1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN claimed
CN-116041153-A Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2023-05-02 CN claimed
CN-115505099-A Epoxy resin containing carbazole structure and preparation method and application thereof 中国石油化工股份有限公司 2022-12-23 CN claimed
CN-115505100-A Epoxy resin based on spirosilafluorene as skeleton and preparation method and application thereof 中国石油化工股份有限公司 2022-12-23 CN claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
CN-108409518-A By active silane to the C-O keys of aromatics, C-N keys and C-S keys without transition metal reductive cleavage 加州理工学院 2018-08-17 CN claimed
CN-104822691-B Transition metal-free reductive cleavage of aromatic C-O, C-N and C-S bonds by reactive silanes 加州理工学院 2018-04-10 CN claimed
US-9908840-B2 Reactions of aromatic substrates with base-activated hydrosilanes-silylations and reductive cleavage CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-03-06 US claimed
WO-2014055586-A1 TRANSITION-METAL FREE REDUCTIVE CLEAVAGE OF AROMATIC C-O, C-N, AND C-S BONDS BY ACTIVATED SILANES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-04-10 WO claimed
US-7018574-B2 condensation polymerization in solvent to form polyphenylene sulfides, then removing volatility via extruder IDEMITSU KOSAN CO., LTD. (JP) 2006-03-28 US claimed
US-6562900-B2 High molecular weight; heat resistance PETROLEUM ENERGY CENTER (JP) 2003-05-13 US claimed
US-20020019501-A1 Production process for polyarylene sulfide PETROLEUM ENERGY CENTER (JP) 2002-02-14 US claimed
US-6316536-B1 WELD STRENGTH AND GOOD MOLDABILITY C IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO claimed
EP-0149958-B1 DECARBOXYLATION OF ROSIN ACIDS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-04-29 EP claimed
EP-0149958-A2 Decarboxylation of rosin acids THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-07-31 EP claimed
US-4515713-A EXTENDER OILS FOR RUBBERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-05-07 US claimed
US-4035424-A Method of preparing symmetrical diarylsulphides DERYAGINA ELEONORA NIKOLAEVNA 1977-07-12 US claimed
JP-62011676-A None JP disclosed
US-4002645-A Bis aromatic anhydrides RAYCHEM CORPORATION (US) 1977-01-11 US disclosed