Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 3/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.54 |
| ▸ | ITGAL | P20701 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703075 | 0.83 | KMT2A (0.71) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL22292158 | 0.82 | KMT2A (0.64) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL15145423 | 0.82 | KMT2A (0.64) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL20356918 | 0.82 | KMT2A (0.64) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL18620488 | 0.82 | KMT2A (0.64) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL15145352 | 0.81 | ITGB2 (0.67) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL15145422 | 0.81 | KMT2A (0.66) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL22647177 | 0.81 | ALDH1A1 (0.57) | ALDH1A1THRB | |
| SCHEMBL15145383 | 0.81 | KMT2A (0.66) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL15145386 | 0.80 | KMT2A (0.65) | KMT2AMEN1HCRTR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227180-A1 | SULFUR AND AMIDE TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USES THEREFOR | SAINT LOUIS UNIVERSITY (US) | 2020-11-12 | — | — | WO | disclosed |