SCHEMBL22648256

SCHEMBL22648256

CCC(=O)C1CCC(C(=O)C(C)C)CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21100174 1.00 NPSR1 (0.32) NPSR1TP53POLB
SCHEMBL26382546 1.00 NPSR1 (0.32) NPSR1TP53POLB
SCHEMBL21100159 0.85 MAPT (0.33) POLB
SCHEMBL800709 0.85
SCHEMBL13197315 0.85 MAPT (0.33) POLB
SCHEMBL21099805 0.85 MAPT (0.33) POLB
SCHEMBL22548934 0.84
SCHEMBL256670 0.83
SCHEMBL25080919 0.82 CHRM2 (0.31)
SCHEMBL21099775 0.82 CHRM2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11236142-B2 Acylated oxyntomodulin peptide analog DONG-A ST CO., LTD. (KR) 2022-02-01 US disclosed
US-20200354425-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG DONG-A ST CO., LTD. (KR) 2020-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354425-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG GLP1R, GIPR, GPR119 NPSR1 195/4885TP53 4679/4885POLB 4739/4885
US-11236142-B2 Acylated oxyntomodulin peptide analog GLP1R, GIPR, GPR119 NPSR1 195/4885TP53 4679/4885POLB 4739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.