Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319289 | 0.92 | CTSL (0.56) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL1734009 | 0.92 | CTSL (0.56) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL13434967 | 0.91 | SIRT2 (0.53) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL3902571 | 0.91 | SIRT2 (0.53) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL133032 | 0.91 | SIRT2 (0.53) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL8054994 | 0.90 | SIRT2 (0.55) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL3996467 | 0.89 | SLC1A3 (0.54) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL3996470 | 0.89 | SLC1A3 (0.54) | SLC1A3SLC1A1LMNASMN1; SMN2SYK | |
| SCHEMBL17865359 | 0.88 | SLC1A3 (0.55) | SLC1A3SLC1A1LMNASMN1; SMN2CTSK | |
| SCHEMBL14985684 | 0.88 | SLC1A3 (0.69) | SLC1A3SLC1A1LMNASMN1; SMN2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225095-A1 | MASP INHIBITORY COMPOUNDS AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-12 | — | — | WO | disclosed |