Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.42 |
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL31223219 | 1.00 | ALDH1A1 (0.79) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28846450 | 1.00 | ALDH1A1 (0.79) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL31223216 | 1.00 | ALDH1A1 (0.79) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28466954 | 0.97 | ALDH1A1 (0.75) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL20569810 | 0.97 | ALDH1A1 (0.75) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL29134574 | 0.97 | ALDH1A1 (0.75) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL29179741 | 0.97 | ALDH1A1 (0.75) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL29179740 | 0.97 | ALDH1A1 (0.75) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28563474 | 0.97 | ALDH1A1 (0.75) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL9150420 | 0.97 | ALDH1A1 (0.75) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 475 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122061204-A | Multistage structure catalyst for catalyzing reduction of carbon dioxide and preparation method thereof | 山东科技大学 | 2026-05-19 | — | — | CN | claimed |
| CN-119684315-B | Crystal form of benzothiophene substituted fused ring compound and preparation method thereof | 苏州盛迪亚生物医药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-121570438-A | Sustained and controlled release preparation process and formula of compound paracetamol and amantadine hydrochloride capsules | 海南亚洲制药股份有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-120130494-A | Ultra-low volume liquid for preventing and controlling sugarcane weeds | 广西南亚热带农业科学研究所 | 2025-06-13 | — | — | CN | claimed |
| CN-119660827-B | Cobalt-free lithium-rich manganese-based oxide material for lithium ion battery and preparation method thereof | 东莞市云帆电子科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119857473-A | Catalyst and method for preparing dimethyl carbonate by catalyzing reaction of methanol and propylene carbonate | 天津科技大学 | 2025-04-22 | — | — | CN | claimed |
| CN-117085076-B | Sugar-free Jiexianghua granule with anti-aging effect and preparation method thereof | 安徽中医药高等专科学校 | 2025-04-01 | — | — | CN | claimed |
| CN-119660827-A | Cobalt-free lithium-rich manganese-based oxide material for lithium ion battery and preparation method thereof | 东莞市云帆电子科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119326779-A | Gemcitabine hydrochloride for injection and preparation method thereof | 郑州大学第一附属医院 | 2025-01-21 | — | — | CN | claimed |
| CN-119118984-A | Preparation process and flow of fatty acid glyceride | 广州至友添加剂有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-105876031-A | Skin-beautifying macadamia nut and peony healthcare scented tea and preparing method thereof | 安徽省天旭茶业有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-105876030-A | Black-tomato yin-nourishing and yang-tonifying peony health-care scented tea and preparing method thereof | 安徽省天旭茶业有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-103130762-B | A kind of method extracting anthocyanidin from indigo fruit | 宁波中药制药股份有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-103386305-B | For the preparation of hydrazine and ammonia nitrogen waste water process catalyst and technique for applying thereof and device | NANJING WEIAN NEW MATERIAL SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2015-09-09 | — | — | CN | claimed |
| CN-103456983-A | Solid thin film electrolyte material and preparation method thereof | UNIV GUILIN ELECTRONIC TECH | 2013-12-18 | — | — | CN | claimed |
| CN-103386305-A | Preparation method, application process and application device of catalyst for treatment of hydrazine and ammonia-nitrogen wastewater | NANJING WEIAN NEW MATERIAL SCIENCE & TECHNOLOGY CO LTD | 2013-11-13 | — | — | CN | claimed |
| CN-103352777-A | Hydrogen engine system | GUANGXI DIKAI SCIENCE & TECHNOLOGY CO LTD | 2013-10-16 | — | — | CN | claimed |
| CN-101182188-B | Method for preparing nano-grade rutile phase RuO2-SnO2 oxide | UNIV FUZHOU | 2010-08-11 | — | — | CN | claimed |
| CN-101182188-A | Method for preparing nano-grade rutile phase RuO2-SnO2 oxide | UNIV FUZHOU (CN) | 2008-05-21 | — | — | CN | claimed |
| CN-1666975-A | Process for preparing dialkylamino ethanol carboxylate and its salts | XIE YUNMAN (CN) | 2005-09-14 | — | — | CN | claimed |