Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 10/20 | 0.49 |
| ▸ | MGAM | O43451 | 9/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.49 |
| ▸ | SI | P14410 | 9/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 4/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101596 | 0.85 | ASAH1 (0.56) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL12648519 | 0.81 | FAAH (0.53) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL12648230 | 0.81 | FAAH (0.53) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL20928041 | 0.80 | ASAH1 (0.53) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL20156704 | 0.77 | ASAH1 (0.51) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL15761538 | 0.77 | FAAH (0.60) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL17875212 | 0.77 | ASAH1 (0.59) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL9419551 | 0.74 | MGAM (0.58) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL20150832 | 0.74 | ASAH1 (0.71) | ASAH1GAAMGAMAMY1ASI | |
| SCHEMBL20664729 | 0.74 | ASAH1 (0.56) | ASAH1GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | DNPEP, PEPD, ANPEP | ASAH1 812/4885GAA 685/4885MGAM 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.