Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827757 | 0.83 | HPGD (0.46) | HCAR2HPGDTSHR | |
| SCHEMBL5358469 | 0.83 | HCAR2 (0.44) | HCAR2 | |
| SCHEMBL21233312 | 0.72 | MAPT (0.45) | HCAR2HPGDTSHR | |
| SCHEMBL22649221 | 0.69 | MAPK1 (0.33) | — | |
| SCHEMBL23001350 | 0.69 | NOTUM (0.32) | HPGD | |
| SCHEMBL2513820 | 0.67 | — | — | |
| SCHEMBL18529859 | 0.67 | HSP90AA1 (0.31) | — | |
| SCHEMBL18695581 | 0.67 | HCAR2 (0.40) | HCAR2 | |
| SCHEMBL18695535 | 0.67 | HCAR2 (0.40) | HCAR2 | |
| SCHEMBL19776269 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227101-A1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |