Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 5/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | RPA1 | P27694 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316081 | 0.87 | MAPK1 (0.34) | MAPK1HCAR3CHEK1RETPDGFRB | |
| SCHEMBL6109157 | 0.85 | ALPL (0.44) | HCAR3ALPLCA12RPA1 | |
| SCHEMBL6211786 | 0.85 | HPGD (0.40) | MAPK1HCAR3CHEK1RETPDGFRB | |
| SCHEMBL24906335 | 0.77 | ALPL (0.50) | MAPK1ALPL | |
| SCHEMBL16629835 | 0.71 | CHEK1 (0.51) | MAPK1CHEK1RETPDGFRBPIM1 | |
| SCHEMBL569002 | 0.70 | — | — | |
| SCHEMBL21233312 | 0.70 | MAPT (0.45) | — | |
| SCHEMBL12011328 | 0.70 | MAPK1 (0.52) | MAPK1HCAR3ALPL | |
| SCHEMBL3452780 | 0.69 | DYRK1A (0.34) | MAPK1ALPLCA12RPA1DYRK1A | |
| SCHEMBL894643 | 0.69 | ALPL (0.50) | HCAR3ALPLCA12RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227101-A1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |