Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | EYA2 | O00167 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978591 | 1.00 | TDP1 (0.48) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL5351865 | 0.98 | BLM (0.45) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL8959877 | 0.95 | TDP1 (0.42) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL29356854 | 0.91 | TDP1 (0.34) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL22053950 | 0.91 | TDP1 (0.58) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL13060101 | 0.91 | TDP1 (0.58) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL22882774 | 0.90 | TDP1 (0.45) | TDP1BLMPMP22KDM4ELMNA | |
| Ethylenediamine SCHEMBL7592869 | 0.89 | TDP1 (0.48) | TDP1BLMPMP22KDM4ELMNA | |
| Ethylenediamine SCHEMBL7966050 | 0.89 | TDP1 (0.48) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL700291 | 0.89 | TDP1 (0.62) | TDP1BLMPMP22KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225447-A1 | PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE | ITM Isotopen Technologien München AG (DE) | 2020-11-12 | — | — | WO | disclosed |