Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351865 | 0.96 | BLM (0.45) | TDP1BLMPMP22CYP2C19KDM4E | |
| SCHEMBL13978591 | 0.95 | TDP1 (0.48) | TDP1BLMPMP22CYP2C19KDM4E | |
| SCHEMBL22649352 | 0.95 | TDP1 (0.48) | TDP1BLMPMP22CYP2C19KDM4E | |
| Ethylenediamine SCHEMBL7966050 | 0.87 | TDP1 (0.48) | TDP1BLMPMP22CYP2C19KDM4E | |
| Ethylenediamine SCHEMBL7592869 | 0.87 | TDP1 (0.48) | TDP1BLMPMP22CYP2C19KDM4E | |
| SCHEMBL27092853 | 0.87 | TDP1 (0.52) | TDP1BLMPMP22CYP2C19KDM4E | |
| SCHEMBL10060617 | 0.87 | MAOA (0.35) | TDP1BLMPMP22CYP2C19KDM4E | |
| SCHEMBL7587742 | 0.87 | TDP1 (0.54) | TDP1BLMPMP22CYP2C19KDM4E | |
| SCHEMBL29223253 | 0.86 | BLM (0.42) | TDP1BLMPMP22CYP2C19KDM4E | |
| SCHEMBL29356854 | 0.85 | TDP1 (0.34) | TDP1BLMPMP22CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482699-A | Multinuclear complexes for x-ray imaging | NYCOMED SALUTAR INC. (US) | 1996-01-09 | — | — | US | claimed |
| US-5482699-A | Multinuclear complexes for x-ray imaging | NYCOMED SALUTAR INC. (US) | 1996-01-09 | — | — | US | disclosed |
| WO-1992017215-A1 | CONTRAST MEDIA | NYCOMED SALUTAR, INC. (US) | 1992-10-15 | — | — | WO | disclosed |