Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | UBE2N | P61088 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14314495 | 0.86 | CYP1A2 (0.44) | KDM4EMAPK1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL4855780 | 0.84 | KDM4E (0.61) | KDM4EHTR1BMAPK1TP53RAB9A | |
| SCHEMBL22650215 | 0.83 | ALDH1A1 (0.49) | KDM4EMAPK1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL17898140 | 0.82 | ALDH1A1 (0.48) | MAPK1SMN1; SMN2HPGDCYP1A2CYP2C19 | |
| SCHEMBL19618911 | 0.80 | KDM4E (0.62) | KDM4EHTR1BMAPK1TP53SMN1; SMN2 | |
| SCHEMBL9353477 | 0.79 | MAPK1 (0.59) | KDM4EMAPK1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1290763 | 0.77 | KDM4E (0.61) | KDM4EHTR1BMAPK1TP53RAB9A | |
| SCHEMBL22650214 | 0.76 | CYP1A2 (0.38) | KDM4EMAPK1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL22650190 | 0.76 | MAPT (0.43) | KDM4EMAPK1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL26655537 | 0.76 | SSTR4 (0.40) | KDM4EMAPK1SMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225330-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2020-11-12 | — | — | WO | disclosed |