SCHEMBL226503

SCHEMBL226503

CCCCOc1ccccc1NC=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
TSHR P16473 2/20 0.51
POLB P06746 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MAPT P10636 5/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GAA P10253 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 4/20 0.46
HTT P42858 3/20 0.46
LMNA P02545 2/20 0.46
PKM P14618 1/20 0.46
NLRP1 Q9C000 1/20 0.46
MEN1 O00255 3/20 0.45
KDM4E B2RXH2 3/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10389742 0.95 KMT2A (0.52) KMT2ATSHRPOLBCYP1A2CYP2C9
SCHEMBL19946517 0.94 KMT2A (0.51) KMT2ATSHRPOLBCYP1A2CYP2C9
SCHEMBL7933003 0.94 KMT2A (0.51) KMT2ATSHRPOLBCYP1A2CYP2C9
SCHEMBL6769638 0.94 KMT2A (0.51) KMT2ATSHRPOLBCYP1A2CYP2C9
SCHEMBL7927147 0.94 KMT2A (0.51) KMT2ATSHRPOLBCYP1A2CYP2C9
SCHEMBL2201555 0.94 KMT2A (0.51) KMT2ATSHRPOLBCYP1A2CYP2C9
SCHEMBL8957741 0.92 ALDH1A1 (0.54) KMT2ATSHRPOLBMAPTMAPK1
SCHEMBL7525333 0.84 ALDH1A1 (0.57) KMT2ATSHRPOLBCYP2C19MAPT
SCHEMBL9264644 0.84 KMT2A (0.55) KMT2ATSHRPOLBCYP1A2CYP2C9
SCHEMBL10871089 0.80 CYP1A2 (0.58) KMT2ATSHRPOLBCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3342771-B1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2020-11-25 EP disclosed
EP-3375780-B1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2020-06-03 EP disclosed
EP-3342771-A1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GlaxoSmithKline Intellectual Property Development Ltd (GB) 2018-07-04 EP disclosed
US-8637220-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and resist film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-01-28 US disclosed
US-20120003583-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-01-05 US disclosed
EP-0307927-B1 Silver halide color photosensitive material FUJI PHOTO FILM CO LTD (JP) 1994-06-22 EP disclosed
US-H1248-H SUPERIOR DESILVERING SPEED, GOOD COLOR REFORMING PROPERTIES AND MINIMUM IMAGE DENSITIES FUJI PHOTO FILM CO., LTD. (JP) 1993-11-02 US disclosed
EP-0295632-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1993-03-03 EP disclosed
US-5064750-A Naphthol amido coupler, bleaching bath of diamino propane teraacetato iron complex FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
EP-0307927-A2 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-03-22 EP disclosed
EP-0295632-A2 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-12-21 EP disclosed