Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 3/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18964486 | 0.88 | MAP4K4 (0.42) | MAP4K4CKS1BSKP1SKP2F2 | |
| SCHEMBL28377656 | 0.88 | MAP4K4 (0.42) | MAP4K4CKS1BSKP1SKP2F2 | |
| SCHEMBL22454874 | 0.88 | MAP4K4 (0.42) | MAP4K4CKS1BSKP1SKP2F2 | |
| SCHEMBL30133739 | 0.88 | MAP4K4 (0.42) | MAP4K4CKS1BSKP1SKP2F2 | |
| SCHEMBL30133744 | 0.88 | MAP4K4 (0.42) | MAP4K4CKS1BSKP1SKP2F2 | |
| SCHEMBL18964485 | 0.88 | MAP4K4 (0.42) | MAP4K4CKS1BSKP1SKP2F2 | |
| SCHEMBL14022306 | 0.83 | FPR2 (0.45) | F2F10PRSS1FPR1FPR2 | |
| SCHEMBL2981427 | 0.83 | MAP4K4 (0.46) | MAP4K4CKS1BSKP1SKP2JAK3 | |
| SCHEMBL18964055 | 0.83 | FPR2 (0.51) | CKS1BSKP1SKP2F10FPR1 | |
| SCHEMBL30337880 | 0.83 | FPR2 (0.51) | CKS1BSKP1SKP2F10FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |