Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 7/20 | 0.34 |
| ▸ | CDK1 | P06493 | 5/20 | 0.34 |
| ▸ | CCND1 | P24385 | 3/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.33 |
| ▸ | CCND3 | P30281 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650362 | 0.85 | CDK4 (0.36) | CDK4CDK1CCND1CCNB1CDK6 | |
| SCHEMBL22650827 | 0.83 | CDK4 (0.39) | CDK4CDK1CCND1CCNB1CDK6 | |
| SCHEMBL29491141 | 0.79 | SMN1; SMN2 (0.37) | CDK1CDK2 | |
| SCHEMBL29827502 | 0.77 | CDK4 (0.51) | CDK4CDK1CCND1CCNB1CDK6 | |
| SCHEMBL15252434 | 0.77 | CDK4 (0.51) | CDK4CDK1CCND1CCNB1CDK6 | |
| SCHEMBL30040812 | 0.76 | CDK4 (0.36) | CDK4CDK1CCND1CCNB1CDK6 | |
| SCHEMBL26066673 | 0.75 | CDK4 (0.40) | CDK4CDK1CCND1CCNB1CDK6 | |
| SCHEMBL30040929 | 0.75 | CDK2 (0.35) | CDK4CDK1CCND1CCNB1CDK2 | |
| SCHEMBL20987162 | 0.74 | EGFR (0.41) | CDK4CDK1CCND1CCNB1CDK6 | |
| SCHEMBL30039849 | 0.74 | EGFR (0.41) | CDK4CDK1CCND1CCNB1CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |