Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 13/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650402 | 0.83 | CDK4 (0.34) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL22650362 | 0.83 | CDK4 (0.36) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL22650828 | 0.81 | CDK4 (0.33) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL22650829 | 0.81 | CDK4 (0.34) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL22650407 | 0.80 | L3MBTL1 (0.37) | CDK1CDK2 | |
| SCHEMBL22650586 | 0.79 | EGFR (0.39) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL22650743 | 0.77 | DAPK1 (0.33) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL29491180 | 0.77 | DAPK1 (0.33) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL29827502 | 0.75 | CDK4 (0.51) | CDK4CCND1CDK1CCNB1EGFR | |
| SCHEMBL15252434 | 0.75 | CDK4 (0.51) | CDK4CCND1CDK1CCNB1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |