Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GCKR | Q14397 | 3/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.32 |
| ▸ | MTOR | P42345 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650368 | 0.78 | ALOX5AP (0.37) | CHRNB2CHRNA4AKR1C3ALOX5APFEN1 | |
| SCHEMBL29462389 | 0.78 | ALOX5AP (0.37) | CHRNB2CHRNA4AKR1C3ALOX5APFEN1 | |
| SCHEMBL22164879 | 0.77 | MAP4K4 (0.48) | CHRNB2CHRNA4MAP4K4 | |
| SCHEMBL17477151 | 0.77 | MAP4K4 (0.48) | CHRNB2CHRNA4MAP4K4 | |
| SCHEMBL1750401 | 0.77 | MAP4K4 (0.48) | CHRNB2CHRNA4MAP4K4 | |
| SCHEMBL30926571 | 0.77 | MAP4K4 (0.48) | CHRNB2CHRNA4MAP4K4 | |
| SCHEMBL24747195 | 0.75 | MCHR1 (0.43) | CHRNB2CHRNA4ALOX5APFEN1MAP4K4 | |
| SCHEMBL29891310 | 0.75 | MCHR1 (0.43) | CHRNB2CHRNA4ALOX5APFEN1MAP4K4 | |
| SCHEMBL30630167 | 0.75 | MCHR1 (0.43) | CHRNB2CHRNA4ALOX5APFEN1MAP4K4 | |
| SCHEMBL29112270 | 0.75 | MCHR1 (0.43) | CHRNB2CHRNA4ALOX5APFEN1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |