Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29491153 | 1.00 | DCTPP1 (0.35) | DCTPP1LMNADAPK1CSNK1ECLK1 | |
| SCHEMBL22650743 | 0.81 | DAPK1 (0.33) | DCTPP1LMNADAPK1 | |
| SCHEMBL29491180 | 0.81 | DAPK1 (0.33) | DCTPP1LMNADAPK1 | |
| SCHEMBL24401874 | 0.78 | KDM4E (0.39) | LMNA | |
| SCHEMBL23598167 | 0.71 | DCTPP1 (0.39) | DCTPP1DAPK1CSNK1ECLK1CLK2 | |
| SCHEMBL19366625 | 0.71 | DCTPP1 (0.36) | DCTPP1DAPK1CSNK1ECLK1CLK2 | |
| SCHEMBL21122393 | 0.69 | DCTPP1 (0.40) | DCTPP1LMNADAPK1CSNK1ECLK1 | |
| SCHEMBL21522868 | 0.69 | NQO2 (0.38) | DCTPP1DAPK1CSNK1ECLK1CLK2 | |
| SCHEMBL2359208 | 0.69 | SMN1; SMN2 (0.47) | CDK5DYRK1ACDK5R1 | |
| SCHEMBL30888966 | 0.69 | NQO2 (0.38) | DCTPP1DAPK1CSNK1ECLK1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |