Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22633565 | 0.90 | GAA (0.61) | SMN1; SMN2GAALMNAHSD17B10HTT | |
| SCHEMBL28518354 | 0.88 | SMN1; SMN2 (0.67) | SMN1; SMN2GAALMNATP53CASP1 | |
| SCHEMBL13405875 | 0.88 | GAA (0.67) | SMN1; SMN2GAALMNATP53HSD17B10 | |
| SCHEMBL12768582 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2GAALMNATP53HSD17B10 | |
| SCHEMBL23649505 | 0.83 | KCNA5 (0.60) | SMN1; SMN2GAALMNAKMT2AALDH1A1 | |
| SCHEMBL3537167 | 0.82 | LMNA (0.54) | SMN1; SMN2GAALMNATP53HSD17B10 | |
| SCHEMBL23648910 | 0.80 | MAPT (0.53) | SMN1; SMN2GAALMNAHTTKMT2A | |
| SCHEMBL23649382 | 0.78 | KCNA5 (0.57) | SMN1; SMN2GAALMNAKMT2AALDH1A1 | |
| SCHEMBL6366763 | 0.78 | SMN1; SMN2 (0.66) | SMN1; SMN2GAALMNATP53HSD17B10 | |
| SCHEMBL13406150 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2GAALMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354327-A1 | COMPOUND HAVING STAT3 INHIBITORY ACTIVITY AND USE THEREOF | CYTUS H&B CO LTD (KR) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354327-A1 | COMPOUND HAVING STAT3 INHIBITORY ACTIVITY AND USE THEREOF | STAT3, JAK2, STAT6 | SMN1; SMN2 4484/4885GAA 2101/4885LMNA 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.