Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | TCF4 | P15884 | 1/20 | 0.60 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180800 | 0.90 | NAMPT (0.78) | NAMPTALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL22633468 | 0.90 | ALDH1A1 (0.72) | NAMPTALDH1A1MAPTEGFRFGFR1 | |
| SCHEMBL30926721 | 0.90 | ALDH1A1 (0.72) | NAMPTALDH1A1MAPTEGFRFGFR1 | |
| Hydrochloric Acid SCHEMBL27181438 | 0.89 | NAMPT (0.76) | NAMPTALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL30926947 | 0.89 | ALDH1A1 (0.64) | NAMPTALDH1A1MAPTPOLBHTT | |
| SCHEMBL27179941 | 0.89 | ALDH1A1 (0.64) | NAMPTALDH1A1MAPTPOLBHTT | |
| SCHEMBL5956144 | 0.88 | NAMPT (0.78) | NAMPTALDH1A1MAPTPOLBHTT | |
| SCHEMBL27180441 | 0.86 | MAPT (0.62) | NAMPTALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL30926790 | 0.86 | MAPT (0.62) | NAMPTALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL30927044 | 0.84 | MEN1 (0.76) | MAPTHTTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354327-A1 | COMPOUND HAVING STAT3 INHIBITORY ACTIVITY AND USE THEREOF | CYTUS H&B CO LTD (KR) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354327-A1 | COMPOUND HAVING STAT3 INHIBITORY ACTIVITY AND USE THEREOF | STAT3, JAK2, STAT6 | NAMPT 1903/4885ALDH1A1 1603/4885MAPT 3283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.