Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23504212 | 0.82 | PIK3CA (0.40) | MTORPIK3CABACE1PIK3R1 | |
| SCHEMBL24746057 | 0.82 | PIK3CA (0.39) | MTORPIK3CAMAP3K12PIK3R1FFAR2 | |
| SCHEMBL30316438 | 0.82 | PIK3CA (0.39) | MTORPIK3CAMAP3K12PIK3R1FFAR2 | |
| SCHEMBL23768373 | 0.81 | LATS1 (0.40) | MTORPIK3CABACE1MAP3K12GAK | |
| SCHEMBL6624674 | 0.80 | MAPT (0.46) | MTORPIK3CABACE1MAP3K12PIK3R1 | |
| SCHEMBL23768374 | 0.78 | CDK4 (0.40) | MTORPIK3CABACE1LATS1SYK | |
| SCHEMBL21017332 | 0.78 | VNN1 (0.39) | MTORPIK3CABACE1MAP3K12LATS1 | |
| SCHEMBL27694801 | 0.77 | POLB (0.65) | MTORPIK3CABACE1LATS1PRKDC | |
| SCHEMBL521049 | 0.76 | PIK3CA (0.56) | MTORPIK3CAPIK3R1 | |
| SCHEMBL23109068 | 0.76 | PIK3CA (0.40) | MTORPIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |