SCHEMBL22650972

SCHEMBL22650972

Clc1cccc(-c2cc3cccc4ccc5cccc2c5c43)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.44
ERBB2 P04626 1/20 0.44
FYN P06241 1/20 0.44
MAOA P21397 1/20 0.44
ACHE P22303 1/20 0.44
AHR P35869 1/20 0.44
ALDH1A1 P00352 5/20 0.39
HPGD P15428 5/20 0.39
HSD17B10 Q99714 5/20 0.39
THRB P10828 1/20 0.39
TSHR P16473 4/20 0.37
CYP3A4 P08684 2/20 0.37
CYP1A1 P04798 2/20 0.37
CYP1B1 Q16678 2/20 0.37
JAK2 O60674 1/20 0.36
TGFBR1 P36897 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
GSK3B P49841 1/20 0.34
MAPK1 P28482 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17412418 0.81 CYP1A2 (0.42) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12955150 0.73 CCR1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28536361 0.73 PDE4D (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL17412413 0.73 KDM4E (0.45) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL10564734 0.73 KDM4E (0.45) CYP1A2ALDH1A1HPGDHSD17B10TSHR
SCHEMBL14241623 0.72 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL14241184 0.72 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL16822385 0.72 CYP1A2 (0.61) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL1535028 0.71 CYP1A2 (0.42) CYP1A2ERBB2FYNMAOAACHE
Benzene SCHEMBL28738256 0.71 CYP1A2 (0.59) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020226295-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-11-12 WO disclosed