Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724764 | 1.00 | USP2 (0.38) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL1947010 | 1.00 | USP2 (0.38) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL3802891 | 0.91 | DGKA (0.43) | LMNAMAPTCYP2D6KDM4ESPHK1 | |
| SCHEMBL11150089 | 0.85 | USP2 (0.40) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL10357997 | 0.85 | USP2 (0.40) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL4394710 | 0.83 | USP2 (0.39) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL3807431 | 0.82 | USP2 (0.37) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL4204713 | 0.80 | USP2 (0.44) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL4204839 | 0.80 | USP2 (0.44) | USP2LMNAMAPTCYP2D6KDM4E | |
| SCHEMBL303130 | 0.80 | USP2 (0.44) | USP2LMNAMAPTCYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367077-B2 | Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof | PEVION BIOTECH, AG (CH) | 2013-02-05 | — | — | US | disclosed |
| CN-101815505-B | Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof | PEVION BIOTECH AG | 2012-09-19 | — | — | CN | disclosed |
| EP-2182923-B1 | VIROSOMES COMPRISING HEMAGGLUTININ DERIVED FROM AN INFLUENZA VIRUS PRODUCED IN A CELL LINE, COMPOSITIONS, METHODS OF MANUFACTURING, USE THEREOF | PEVION BIOTECH AG (CH) | 2012-01-04 | — | — | EP | disclosed |
| US-20110045057-A1 | Virosomes Comprising Hemagglutinin Derived from an Influenza Virus Produced in a Cell Line, Compositions, Methods of Manufacturing, Use Thereof | PEVION BIOTECH, AG (CH) | 2011-02-24 | — | — | US | disclosed |
| CN-101815505-A | Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof | PEVION BIOTECH AG | 2010-08-25 | — | — | CN | disclosed |
| EP-2014279-A1 | Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof | Pevion Biotech AG (CH) | 2009-01-14 | — | — | EP | disclosed |