Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031970 | 0.89 | ESR1 (0.65) | ESR1ESR2MAPTMEN1LMNA | |
| SCHEMBL822520 | 0.89 | ESR1 (0.52) | ESR1ESR2MAPTHTTNPC1 | |
| SCHEMBL13072627 | 0.87 | ESR1 (0.65) | ESR1ESR2MAPTMEN1LMNA | |
| SCHEMBL23034829 | 0.86 | ESR1 (0.64) | ESR1ESR2MAPTMEN1LMNA | |
| SCHEMBL14287530 | 0.85 | ESR1 (0.49) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL21075509 | 0.85 | ESR1 (0.49) | ESR1ESR2MAPTMEN1LMNA | |
| SCHEMBL1847909 | 0.84 | ESR1 (0.78) | ESR1ESR2MAPTMEN1LMNA | |
| SCHEMBL29462974 | 0.84 | ESR1 (0.78) | ESR1ESR2MAPTMEN1LMNA | |
| SCHEMBL21405708 | 0.84 | ESR1 (0.61) | ESR1ESR2MAPTMEN1LMNA | |
| SCHEMBL21405706 | 0.84 | ESR1 (0.61) | ESR1ESR2MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354512-A1 | POLYMER, COMPOSITION, MOLDED ARTICLE, CURED PRODUCT, AND LAMINATE | JSR CORPORATION (JP) | 2020-11-12 | — | — | US | disclosed |