SCHEMBL822520

SCHEMBL822520

COc1ccc(C2(c3ccc(OC(C)=O)c(C)c3)c3ccccc3-c3ccccc32)cc1C

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
CHRM5 P08912 4/20 0.44
TNFSF11 O14788 1/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 3/20 0.38
NR3C1 P04150 1/20 0.37
BACE1 P56817 1/20 0.37
JUN P05412 1/20 0.36
NFKB1 P19838 1/20 0.36
FPR1 P21462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14287530 0.91 ESR1 (0.49) ESR1ESR2CHRM5MAPTNPC1
SCHEMBL22651232 0.89 ESR1 (0.70) ESR1ESR2CHRM5MAPTNPC1
SCHEMBL18415977 0.88 ESR1 (0.61) ESR1ESR2CHRM5MAPTNPC1
SCHEMBL13446409 0.87 ESR1 (0.49) ESR1ESR2CHRM5TNFSF11TSHR
SCHEMBL14700590 0.86 CHRM5 (0.40) ESR1ESR2CHRM5TNFSF11TSHR
SCHEMBL14700552 0.86 ALOX5 (0.41) ESR1ESR2CHRM5TSHRMAPT
SCHEMBL21075509 0.86 ESR1 (0.49) ESR1ESR2CHRM5MAPTNPC1
SCHEMBL12578507 0.86 ESR1 (0.49) ESR1ESR2CHRM5MAPT
SCHEMBL14700520 0.86 CFD (0.39) ESR1ESR2CHRM5TSHRBACE1
SCHEMBL12602049 0.84 ESR1 (0.54) ESR1ESR2CHRM5TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239962-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE IDEMITSU KOSAN CO.,LTD. (JP) 2024-07-18 US disclosed
US-20230192951-A1 POLYCARBONATE RESIN, AND OPTICAL LENS AND OPTICAL FILM USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-06-22 US disclosed
US-20230192951-A1 POLYCARBONATE RESIN, AND OPTICAL LENS AND OPTICAL FILM USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-06-22 US disclosed
EP-3750939-B1 POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY MITSUBISHI GAS CHEMICAL CO (JP) 2023-05-24 EP disclosed
US-20230046996-A1 POLYCARBONATE/POLYORGANOSILOXANE COPOLYMER AND RESIN COMPOSITION INCLUDING SAID COPOLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230052441-A1 POLYCARBONATE/POLYORGANOSILOXANE COPOLYMER AND RESIN COMPOSITION INCLUDING SAID COPOLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230038766-A1 POLYCARBONATE/POLYORGANOSILOXANE COPOLYMER AND RESIN COMPOSITION INCLUDING SAID COPOLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-09 US disclosed
EP-4071195-A1 POLYCARBONATE/POLYORGANOSILOXANE COPOLYMER AND RESIN COMPOSITION INCLUDING SAID COPOLYMER Idemitsu Kosan Co., Ltd (JP) 2022-10-12 EP disclosed
WO-2021112259-A1 POLYCARBONATE/POLYORGANOSILOXANE COPOLYMER AND RESIN COMPOSITION INCLUDING SAID COPOLYMER 出光興産株式会社 2021-06-10 WO disclosed
WO-2021112260-A1 POLYCARBONATE/POLYORGANOSILOXANE COPOLYMER AND RESIN COMPOSITION INCLUDING SAID COPOLYMER 出光興産株式会社 2021-06-10 WO disclosed
US-20080146759-A1 Sulfur-Containing Compound, Method for Producing Same, Sulfur-Containing Polymer, and Optical Material IDEMITSU KOSAN CO., LTD (JP) 2008-06-19 US disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-7317067-B2 Polycarbonate copolymer, and heat resistant parts comprising the same TEIJIN CHEMICALS (JP) 2008-01-08 US disclosed
US-7317067-B2 Polycarbonate copolymer, and heat resistant parts comprising the same TEIJIN CHEMICALS (JP) 2008-01-08 US disclosed
US-20070293606-A1 Infrared Absorption Filter OSAKA GAS CO., LTD. (JP) 2007-12-20 US disclosed
US-20070293606-A1 Infrared Absorption Filter OSAKA GAS CO., LTD. (JP) 2007-12-20 US disclosed
US-RE39753-E1 Single oriented film, at wavelengths of 450 nm and 550 nm of retardation, of a polycarbonate polystyrene blend; liquid crystal display TEIJIN LIMITED (JP) 2007-07-31 US disclosed
EP-1804093-A1 INFRARED ABSORBING FILTER OSAKA GAS CO., LTD. (JP) 2007-07-04 EP disclosed
US-7223451-B2 Polycarbonate-based oriented film and retardation film TEIJIN LIMITED (JP) 2007-05-29 US disclosed
US-20070026334-A1 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2007-02-01 US disclosed