Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrogen Sulfide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15400 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8856001 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL10409095 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL121448 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11515885 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7511711 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL10655988 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL9485182 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL11027200 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3659162 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351724-B1 | PROCESS FOR PRODUCING p-DICHLOROBENZENE | TOSOH CORP (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8524957-B2 | Process for producing p-dichlorobenzene | TOSOH CORPORATION (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20110207976-A1 | PROCESS FOR PRODUCING P-DICHLOROBENZENE | TOSOH CORPORATION (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2351724-A1 | PROCESS FOR PRODUCING p-DICHLOROBENZENE | Tosoh Corporation (JP) | 2011-08-03 | — | — | EP | disclosed |