Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 18/20 | 0.56 |
| ▸ | BRAF | P15056 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22612964 | 0.88 | RAF1 (0.57) | RAF1BRAF | |
| SCHEMBL22652917 | 0.86 | RAF1 (0.56) | RAF1BRAF | |
| SCHEMBL30439590 | 0.77 | RAF1 (0.75) | RAF1BRAF | |
| SCHEMBL26782937 | 0.77 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL22612814 | 0.77 | RAF1 (0.75) | RAF1BRAF | |
| SCHEMBL22612815 | 0.77 | RAF1 (0.75) | RAF1BRAF | |
| SCHEMBL22612812 | 0.77 | RAF1 (0.75) | RAF1BRAF | |
| SCHEMBL30439586 | 0.77 | RAF1 (0.75) | RAF1BRAF | |
| SCHEMBL22612945 | 0.77 | RAF1 (0.65) | RAF1BRAF | |
| SCHEMBL25601525 | 0.76 | RAF1 (0.57) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227020-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2020-11-12 | — | — | WO | disclosed |