Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775200 | 0.81 | SLC7A5 (0.50) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL22775179 | 0.77 | SLC7A5 (0.46) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL22775176 | 0.77 | SLC7A5 (0.46) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL22775828 | 0.77 | GRB2 (0.48) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL22775395 | 0.76 | GRM8 (0.53) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL2310526 | 0.72 | SLC7A5 (0.83) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL14780597 | 0.71 | USP2 (0.45) | SLC7A5PKMPTGS1ALPIXIAP | |
| Phenylalanine SCHEMBL7050575 | 0.71 | SLC7A5 (0.96) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL288375 | 0.69 | SLC7A5 (0.71) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL43851 | 0.69 | SLC7A5 (0.71) | SLC7A5PKMPTGS1ALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227105-A1 | ANTI-BCMA ANTIBODY CONJUGATES | SUTRO BIOPHARMA, INC. (US) | 2020-11-12 | — | — | WO | disclosed |