⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23220249 | 0.90 | THRB (0.63) | — | |
| SCHEMBL2841738 | 0.90 | THRB (0.63) | — | |
| Hydrochloric Acid SCHEMBL28131943 | 0.88 | THRB (0.61) | — | |
| SCHEMBL1161063 | 0.78 | THRB (0.47) | — | |
| SCHEMBL26143584 | 0.77 | THRB (0.42) | — | |
| SCHEMBL31141158 | 0.77 | THRB (0.46) | — | |
| SCHEMBL16039852 | 0.76 | — | — | |
| SCHEMBL31460263 | 0.75 | THRB (0.41) | — | |
| SCHEMBL13126727 | 0.75 | THRB (0.45) | — | |
| SCHEMBL10206074 | 0.75 | THRB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | disclosed |
| CN-116444515-A | Di-ring derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115974897-A | Bicyclic derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-112368283-B | Bicyclic derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| EP-3740487-A1 | BENZAMIDE COMPOUNDS | Recurium IP Holdings, LLC (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3737681-A1 | BENZAMIDE COMPOUNDS | Recurium IP Holdings, LLC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3737672-A1 | BENZAMIDE COMPOUNDS | Recurium IP Holdings, LLC (US) | 2020-11-18 | — | — | EP | disclosed |