SCHEMBL22654012

SCHEMBL22654012

[CH2]CC1CC2(CCCCC2)C(=O)O1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 15/20 0.46
TMEM97 Q5BJF2 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16151276 0.81 HTR7 (0.46) HTR7TMEM97
SCHEMBL19777175 0.81 HTR7 (0.46) HTR7TMEM97
SCHEMBL22672852 0.81 HTR7 (0.46) HTR7TMEM97
SCHEMBL12344742 0.81 HTR7 (0.47) HTR7TMEM97
SCHEMBL19786710 0.79 HTR7 (0.44) HTR7TMEM97
SCHEMBL16151042 0.79 HTR7 (0.44) HTR7TMEM97
SCHEMBL20510314 0.79 HTR7 (0.50) HTR7TMEM97
SCHEMBL21643217 0.79 HTR7 (0.50) HTR7TMEM97
SCHEMBL16150635 0.79 HTR7 (0.51) HTR7TMEM97
SCHEMBL17435911 0.78 HTR7 (0.47) HTR7TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3738955-A1 NOVEL 5-HYDROXYTRYPTAMINE RECEPTOR 7 ACTIVITY MODULATORS AND THEIR METHOD OF USE Temple University Of The Commonwealth System Of Higher Education (US) 2020-11-18 EP disclosed