SCHEMBL22657805

SCHEMBL22657805

COCCOCCOCCOCCOCCOCCOCCOCCC(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ GAA P10253 1/20 0.49
▸ GLP1R P43220 8/20 0.45
▸ FOLH1 Q04609 2/20 0.44
▸ TDP1 Q9NUW8 2/20 0.42
▸ ATM Q13315 1/20 0.42
▸ SUCNR1 Q9BXA5 5/20 0.42
▸ POLB P06746 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22657806 1.00 MEN1 (0.49) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL13936448 0.91 GLP1R (0.54) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL13936450 0.91 GLP1R (0.54) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL31045346 0.91 CAPN1 (0.46) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL27145930 0.91 CAPN1 (0.46) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL21713193 0.91 CAPN1 (0.46) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL21713192 0.91 CAPN1 (0.46) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL27150954 0.91 CAPN1 (0.46) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL27145928 0.91 CAPN1 (0.46) MEN1KMT2AGAAGLP1RFOLH1
SCHEMBL20797923 0.90 MEN1 (0.50) MEN1KMT2AGAAGLP1RFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220409734-A1 ANTIBODY DRUG CONJUGATES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-12-29 — — US disclosed
EP-3965891-A1 ANTIBODY DRUG CONJUGATES Takeda Pharmaceutical Company Limited (JP) 2022-03-16 — — EP disclosed
CN-114173824-A Antibody drug conjugates 武田药品工业株式会社 2022-03-11 — — CN disclosed
WO-2020229982-A1 ANTIBODY DRUG CONJUGATES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-11-19 — — WO disclosed
WO-2020229982-A1 ANTIBODY DRUG CONJUGATES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-11-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220409734-A1 ANTIBODY DRUG CONJUGATES STING1, CGAS, TBK1 MEN1 2117/4885KMT2A 3057/4885GAA 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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