Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HK2 | P52789 | 5/20 | 0.43 |
| ▸ | HK1 | P19367 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | PYGB | P11216 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1542063 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL15966301 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL1548304 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL23631140 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL15966283 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL22988698 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL1548307 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL15965645 | 1.00 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| Sulfuric Acid SCHEMBL21062202 | 0.98 | CA1 (0.46) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL10325036 | 0.84 | KDM4E (0.49) | CA1CA2CA9CA12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366853-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | EXTHERA MEDICAL CORPORATION (US) | 2024-11-07 | — | — | US | disclosed |
| US-12090261-B2 | Method for modulating endothelial glycocalyx structure | EXTHERA MEDICAL CORPORATION (US) | 2024-09-17 | — | — | US | disclosed |
| EP-3969014-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | ExThera Medical Corporation (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-113825517-A | Methods of modulating endothelial glycocalyx structure | 艾克塞拉医疗公司 | 2021-12-21 | — | — | CN | disclosed |
| WO-2020231830-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | EXTHERA MEDICAL CORPORATION (US) | 2020-11-19 | — | — | WO | disclosed |