Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HK2 | P52789 | 5/20 | 0.42 |
| ▸ | HK1 | P19367 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PYGB | P11216 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548304 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL1542063 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL1548307 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL22988698 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL15966283 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL23631140 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL15965645 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL22658152 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL15966301 | 0.98 | CA1 (0.47) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL10325036 | 0.83 | KDM4E (0.49) | CA1CA2CA9CA12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11806362-B2 | Heparin and heparan sulphate oligosaccharides | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-11-07 | — | — | US | disclosed |
| CN-111741980-B | Heparin and heparan sulfate oligosaccharides | 新加坡科技研究局 | 2023-02-17 | — | — | CN | disclosed |
| US-11331337-B2 | Heparin and heparan sulphate oligosaccharides | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-05-17 | — | — | US | disclosed |
| US-20210161945-A1 | HEPARIN AND HEPARAN SULPHATE OLIGOSACCHARIDES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-06-03 | — | — | US | disclosed |
| EP-3724238-A1 | HEPARIN AND HEPARAN SULPHATE OLIGOSACCHARIDES | Agency for Science, Technology and Research (SG) | 2020-10-21 | — | — | EP | disclosed |
| CN-111741980-A | Heparin and heparan sulfate oligosaccharides | 新加坡科技研究局 | 2020-10-02 | — | — | CN | disclosed |
| WO-2019117807-A1 | HEPARIN AND HEPARAN SULPHATE OLIGOSACCHARIDES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-06-20 | — | — | WO | disclosed |