Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CDK9 | P50750 | 2/20 | 0.48 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664610 | 0.88 | GSK3B (0.45) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| SCHEMBL29533271 | 0.88 | GSK3B (0.45) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| Hydrochloric Acid SCHEMBL22659461 | 0.87 | GSK3B (0.50) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| Hydrochloric Acid SCHEMBL29533430 | 0.87 | GSK3B (0.50) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| SCHEMBL22659961 | 0.84 | GSK3B (0.48) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| SCHEMBL22659808 | 0.82 | BTK (0.53) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| SCHEMBL29533525 | 0.82 | BTK (0.53) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| SCHEMBL29533591 | 0.82 | BTK (0.52) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| SCHEMBL22659379 | 0.82 | BTK (0.52) | GSK3BMAPK14GSK3ACDK1CDK2 | |
| SCHEMBL22659397 | 0.81 | GSK3B (0.47) | GSK3BMAPK14GSK3ACDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232330-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. (US) | 2020-11-19 | — | — | WO | disclosed |