Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659808 | 1.00 | BTK (0.53) | BTKLCKMAPK14GSK3BABL1 | |
| SCHEMBL22664846 | 0.89 | BTK (0.51) | BTKLCKMAPK14GSK3BABL1 | |
| Hydrochloric Acid SCHEMBL22659441 | 0.88 | BTK (0.51) | BTKLCKMAPK14GSK3BABL1 | |
| Hydrochloric Acid SCHEMBL29533241 | 0.88 | BTK (0.51) | BTKLCKMAPK14GSK3BABL1 | |
| SCHEMBL22659452 | 0.88 | BTK (0.53) | BTKLCKMAPK14GSK3BABL1 | |
| SCHEMBL29533081 | 0.88 | BTK (0.53) | BTKLCKMAPK14GSK3BABL1 | |
| SCHEMBL29533826 | 0.88 | BTK (0.53) | BTKLCKMAPK14GSK3BCDK1 | |
| SCHEMBL22659710 | 0.88 | BTK (0.53) | BTKLCKMAPK14GSK3BCDK1 | |
| SCHEMBL22659379 | 0.86 | BTK (0.52) | BTKLCKMAPK14GSK3BABL1 | |
| SCHEMBL29533591 | 0.86 | BTK (0.52) | BTKLCKMAPK14GSK3BABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969124-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2022-03-23 | — | — | EP | disclosed |